Custom Peptides
Cayman Chemical RamosetronhydrochlorIde 10mg
A potent and selective antagonist of the serotonin (5-HT) receptor subtype 5-HT3 (Ki = 0.06 nM); has little or no effect at other 5-HT receptor subtypes or at adrenergic or histamine receptors
Cayman Chemical ngenol-3-ngelate 10mg
A hydrophobic diterpene ester that rapidly induces cell death in proliferating keratinocytes through plasma membrane and mitochondrial disruption; causes inflammation due, at least in part, to activation of PKC, leading to antibody-dependent cellular cytotoxicity
Cayman Chemical 5-EAPBhydrochlorIde 10mg
An analytical reference standard categorized as a benzofuran; increases conditioned place preference for the 5-EAPB-paired chamber and reinforcement in a self-administration test in rats; has been found in seized samples suspected of containing NPS; associated with fatality; intended for research and forensic applications
Cayman Chemical -CromakalIm 10mg
An activator of the ATP-sensitive K+ channels that displays anti-ischemic (EC25 = 8.9 μM) and cardioprotective (IC50 = 0.03 μM) effects in rat hearts
Cayman Chemical 13 14dIhydro PROSGlnDN F 10mg
13,14-dihydro PGF1α is a potential metabolite of PGF1α.{2346} Its biological activity has not been reported. The corresponding compound in the E1 series (13,14-dihydro PGE1) retains biological activity similar to PGE1.{4168}
Cayman Chemical 1MyrIstoyl2Oleoyl3Docosa 10mg
A triacylglycerol; has been used as a reagent to study the regioselectivity of thermal chlorination reactions between triacylglycerols and organochlorines that result in the formation of MCPD diesters
Cayman Chemical AmastatInhydrochlorIde 10mg
A slow, tight binding, competitive aminopeptidase (AP) inhibitor, first described as an inhibitor of AP-A (glutamyl AP; IC50 = 0.54 UG/ml) but not of AP-B (arginine AP); also inhibits AP-N (AP-M, alanyl AP; Ki = 20-200 nM), leucyl-cystinyl AP (Ki = 20-220 nM), and endoplasmic reticulum AP 1 (Ki = 41.8 µM)
Cayman Chemical SureLIghtB-PhycoerythrInB 10mg
Because of its high quantum yield, B-PE is considered the world’s brightest fluorophore. It is compatible with commonly available lasers and gives exceptional results in flow cytometry, Luminex and immunofluorescent staining. B-PE is also less “sticky” than common synthetic fluorophores and therefore gives less background interference. Uses: Flow cytometry, Fluorescence-activated cell sorting, Custom Antibody labeling, Luminex, and T Cell labeling
Cayman Chemical TrIbulosIdehydrate 10mg
A flavonoid; active against M. madagascariense and M. indicus pranii (MICs = 0.8 and 1.6 mg/ml); scavenges DPPH radicals at 63.7-75.2 mg/ml
Cayman Chemical MJ33lIthIum salt 10mg
A selective, reversible inhibitor of the acidic, calcium-independent (ai)PLA2 activity of Prdx6, with optimal inhibition achieved at an MJ33 concentration of 3 mol%; blocks the degradation of DPPC in both whole lung and isolated alveolar type II epithelial cells
Cayman Chemical DaunorubIcInon 10mg
An aglcyone form of the antitumor antibiotic daunorubicin; has been used as a starting material in the synthesis of anticancer agents
Cayman Chemical ParaxnthIn 10mg
An active metabolite of caffeine; an adenosine A1 and A2 receptor antagonist (Kis = 35 and 22 µM, respectively); increases striatal cGMP and extracellular striatal dopamine levels and locomotor activity, as well as inhibits motor depression induced by CPA or CGS 21680 in rats not habituated to caffeine at 30 mg/kg; promotes wakefulness and increases locomotor activity and core temperature in narcoleptic transgenic mice without increasing behavioral anxiety
Cayman Chemical EstropIpate 10mg
A piperazine salt form of estrone 3-sulfate; inhibits OATP1B1 selectively over OATP1B3 (IC50s = 0.06 and 19.32 µM, respectively)
Cayman Chemical RaxatrIgInhydrochlorIde 10mg
An inhibitor of voltage-gated sodium channels (IC50s = 22, 13, 23, 10, 84, 15, 32, and 6 µM for Nav1.1- Nav1.8 channels); has state-dependent activity at the Nav1.7 channel (IC50s = 6.3 and 54 µM for open/inactivated and closed/resting states); decreases pain behavior in an OD1 mouse pain model